当然,风险亦不容忽视。Infigratinib是泛FGFR1-4抑制剂,对FGFR1等的抑制可能引起高磷血症等副作用。3期试验中约有4%患者出现轻度、短暂的高磷血症。在儿科长期用药的背景下,其安全性仍需更严格的监测,监管的要求也会更严格。
The capacity of each node (how many points it can hold before splitting) controls the shape of the tree. A low capacity means nodes split early, producing a deep tree with many small cells. A high capacity means nodes tolerate more points before splitting, producing a shallow tree with larger cells.
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"command": "cmdValidatePromo",
The announcements come shortly after a new class-action lawsuit was filed against Bumble over the January data breach. It's also after Bumble announced it's sunsetting the Opening Moves feature in Mexico and Australia. Opening Moves is a feature meant to move Bumble away from its "women making the first move" ethos by allowing men to message women first.